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High risk of a severe reaction to the HIV drug abacavir.Carrying HLA-B*57:01 means abacavir can trigger a dangerous hypersensitivity reaction. Screening for this variant before prescribing is standard practice.MedicationMedication responseHLA-B
Plavix is about 50% less effective for you.Poor metabolizers of clopidogrel (Plavix) may not get the intended protection after a cardiac event. A clinician can choose an alternative blood thinner that works with your genetics.MedicationMedication responseCYP2C19
You need about 30% less warfarin than average.A VKORC1 variant makes you more sensitive to warfarin, so a standard dose could thin your blood too much. Sharing this lets a clinician start lower and avoid trial and error.MedicationMedication responseVKORC1
Higher chance of muscle pain on common statins.SLCO1B1 affects how the body clears statins. Certain variants raise the risk of muscle aches and, rarely, muscle damage, so a clinician may pick a different statin or dose.MedicationMedication responseSLCO1B1

Educational reference only. Not a diagnosis. Discuss significant findings with a clinician.