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Gene Explorer / HLA-B

HLA-B

Medication responseMedicationStrong evidenceHigh attention

High risk of a severe reaction to the HIV drug abacavir.

Carrying HLA-B*57:01 means abacavir can trigger a dangerous hypersensitivity reaction. Screening for this variant before prescribing is standard practice.

Also known as: HLA-B*57:01, abacavir

Associated with

  • abacavir
  • HIV
  • hypersensitivity
  • allergy
  • pharmacogenomics

Educational only. Significant findings should be reviewed with a clinician.

More Medication genes

Educational reference only — not a diagnosis. Discuss significant findings with a clinician.