Gene Explorer / SLCO1B1

SLCO1B1

Medication responseMedicationModerate evidenceNotable

Higher chance of muscle pain on common statins.

SLCO1B1 affects how the body clears statins. Certain variants raise the risk of muscle aches and, rarely, muscle damage, so a clinician may pick a different statin or dose.

Also known as: statin

Associated with

  • statin
  • simvastatin
  • muscle pain
  • cholesterol
  • pharmacogenomics

Educational only. Significant findings should be reviewed with a clinician.

Educational reference only — not a diagnosis. Discuss significant findings with a clinician.