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Gene Explorer / BRCA1

BRCA1

Disease riskCancerStrong evidenceHigh attention

About 5× higher lifetime risk of breast and ovarian cancer.

BRCA1 normally helps repair damaged DNA. A harmful variant raises the lifetime risk of breast and ovarian cancer well above average, which is why carriers benefit from earlier and more frequent screening.

Also known as: breast cancer 1

Associated with

  • breast cancer
  • ovarian cancer
  • hereditary cancer
  • DNA repair

Educational only. Significant findings should be reviewed with a clinician.

More Cancer genes

Educational reference only — not a diagnosis. Discuss significant findings with a clinician.