PCSK9

TraitHeart diseaseStrong evidenceBackground

Naturally lower LDL cholesterol - a genetic “superpower” for heart health.

Some PCSK9 variants keep LDL cholesterol low lifelong without medication. Drug developers copied the biology for cholesterol-lowering therapies - one of the best examples of a fun gene with serious medical upside.

Associated with

cholesterol
LDL
heart health
longevity

Educational only. Significant findings should be reviewed with a clinician.

More Heart disease genes

Educational reference only — not a diagnosis. Discuss significant findings with a clinician.