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Gene Explorer / APOE

APOE

Disease riskNeurologicalStrong evidenceNotable

One copy of APOE e4 raises Alzheimer’s risk about 30%.

APOE e4 is the most common genetic risk factor for late-onset Alzheimer’s. It shifts the odds without deciding them, and sleep, exercise and cardiovascular health all matter.

Also known as: ApoE4, APOE e4

Associated with

  • alzheimer
  • dementia
  • cognitive decline
  • brain health

Educational only. Significant findings should be reviewed with a clinician.

More Neurological genes

Educational reference only — not a diagnosis. Discuss significant findings with a clinician.